Rapamycin inhibits intestinal tumor formation and growth [PreClinical]
Original report from 2 Minute Medicine: 1. Rapamycin (rapa) inhibited tumor initiation in Adenomatous polyposis coli gene (Apc)-deficient mouse intestinal epithelial cells, and enhanced survival in a...
View ArticleGenetically engineered lymphocytes inhibit Hepatitis C virus replication in...
Original report from 2 Minute Medicine: 1. Activated suicide gene modified lymphocytes (SGMLs) inhibit Hepatitis C virus (HCV) replication multiple in vitro models of infection. 2. At low...
View ArticleTumor-specific mutant antigens are potential targets for cancer therapy...
Original report from 2 Minute Medicine: 1. Following checkpoint blockade therapy (CBT) in a mouse sarcoma model, two dominant tumor-specific mutant antigen (TSMA) targets of CD8+ T cells were...
View ArticleLSD1 inhibition reduces herpesvirus infection and recurrence in animals...
Original report from 2 Minute Medicine: 1. Pharmaceutical inhibition of lysine-specific demethylase 1 (LSD1) reduced primary infection of herpes simplex virus (HSV), shedding, and reactivation in...
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